Publications

Li, Z., Zhao, S., Nelakanti, R.V., Lin, K., Wu, T., Alderman, M.H., Guo, C., Wang, P., Zhang, M., Min, W., Jiang, Z., Wang, Y., Li, H., Xiao, A.Z. (2020). N6-methyladenine in DNA antagonizes SATB1 in early development.  Nature. doi: 10.1038/s41586-020-2500-9

Zhang, M., Yang, S., Nelakanti, R., Zhao, W., Liu, G., Li, Z., Liu, X., Wu, T., Xiao, A., Li, H. (2020). Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA. Cell Research. doi: 10.1038/s41422-019-0237-5

Alderman, M.H., Xiao, A.Z. (2019). N(6)-Methyladenine in eukaryotes. Cellular and Molecular Life Sciences. doi: 10.1007/s00018-019-03146-w

Xie, Q., Wu, T.P., Gimple, R.C., Li, Z., Prager, B.C., Wu, Q., Yu, Y., Wang, P., Wang, Y., Gorkin, D.U., Zhang, C., Dowiak, A.V., Lin, K., Zeng, C., Sui, Y., Kim, L.J.Y., Miller, T.E., Jiang, L., Lee, C.H., Huang, Z., Fang, X., Zhai, K., Mack, S.C., Sander, M., Bao, S., Kerstetter-Fogle, A.E., Sloan, A.E., Xiao, A.Z., Rich, J.N. (2018). N6-methyladenine DNA Modification in Glioblastoma. Cell. doi: 10.1016/j.cell.2018.10.006

Zhu, S., Beaulaurier, J., Deikus, G., Wu, T.P., Strahl, M., Hao, Z., Luo, G., Gregory, J.A., Chess, A., He, C., Xiao, A., Sebra, R., Schadt, E.E., Fang, G. (2018). Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing. Genome Research. doi: 10.1101/gr.231068.117

Lin, K., Xiao, A.Z. (2017). Quality control towards the application of induced pluripotent stem cells. Current Opinion in Genetics and Development. doi: 10.1016/j.gde.2017.07.006

Choi, J., Huebner, A.J., Clement, K., Walsh, R.M., Savol, A., Lin, K., Gu, H., Di Stefano, B., Brumbaugh, J., Kim, S.-Y., Sharif, J., Rose, C.M., Mohammad, A., Odajima, J., Charron, J., Shioda, T., Gnirke, A., Gygi, S., Koseki, H., Sadreyev, R.I., Xiao, A., Meissner, A., Hochedlinger, K. (2017). Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells. Nature. doi: 10.1038/nature23274

Wu, T.P., Wang, T., Seetin, M.G., Lai, Y., Zhu, S., Lin, K., Liu, Y., Byrum, S.D., Mackintosh, S.G., Zhong, M., Tackett, A., Wang, G., Hon, L.S., Fang, G., Swenberg, J.A., Xiao, A.Z. (2016). DNA methylation on N6-adenine in mammalian embryonic stem cells. Nature. doi: 10.1038/nature17640

Dan, J., Yang, J., Liu, Y., Xiao, A., Liu, L. (2015). Roles for Histone Acetylation in Regulation of Telomere Elongation and Two-cell State in Mouse ES Cells. Journal of Cellular Physiology. doi: 10.1002/jcp.24980

Liu, Y., Xiao, A. (2015). Adaption by Rewiring Epigenetic Landscapes. Cell Stem Cell. doi: 10.1016/j.stem.2015.08.015

Benchetrit, H., Herman, S., Van Wietmarschen, N., Wu, T., Makedonski, K., Maoz, N., Yom Tov, N., Stave, D., Lasry, R., Zayat, V., Xiao, A., Lansdorp, P.M., Sebban, S., Buganim, Y. (2015). Extensive Nuclear Reprogramming Underlies Lineage Conversion into Functional Trophoblast Stem-like Cells. Cell Stem Cell. doi: 10.1016/j.stem.2015.08.006

Dan, J., Liu, Y., Liu, N., Chiourea, M., Okuka, M., Wu, T., Ye, X., Mou, C., Wang, L., Wang, L., Yin, Y., Yuan, J., Zuo, B., Wang, F., Li, Z., Pan, X., Yin, Z., Chen, L., Keefe, D.L., Gagos, S., Xiao, A., Liu, L. (2014). Rif1 Maintains Telomere Length Homeostasis of ESCs by Mediating Heterochromatin Silencing. Developmental Cell. doi: 10.1016/j.devcel.2014.03.004

Tseng, Z., Wu, T., Liu, Y., Zhong, M., Xiao, A. (2014). Using native chromatin immunoprecipitation to interrogate histone variant protein deposition in embryonic stem cells. Methods in Molecular Biology. doi: 10.1007/978-1-4939-0992-6_2

Wu, T., Liu, Y., Wen, D., Tseng, Z., Tahmasian, M., Zhong, M., Rafii, S., Stadtfeld, M., Hochedlinger, K., Xiao, A. (2014). Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs. Cell Stem Cell. doi: 10.1016/j.stem.2014.06.004

Buganim, Y., Markoulaki, S., Van Wietmarschen, N., Hoke, H., Wu, T., Ganz, K., Akhtar-Zaidi, B., He, Y., Abraham, B.J., Porubsky, D., Kulenkampff, E., Faddah, D.A., Shi, L., Gao, Q., Sarkar, S., Cohen, M., Goldmann, J., Nery, J.R., Schultz, M.D., Ecker, J.R., Xiao, A., Young, R.A., Lansdorp, P.M., Jaenisch, R. (2014). The developmental potential of iPSCs is greatly influenced by reprogramming factor selection. Cell Stem Cell. doi: 10.1016/j.stem.2014.07.003

Liu, Y., Xiao, A. (2011). Epigenetic regulation in neural crest development. Birth Defects Research Part A - Clinical and Molecular Teratology. doi: 10.1002/bdra.20797